Collaborative Alliance for Pancreatic Education and Research
What is APPRENTICE?
APPRENTICE is an international multi-center study on Acute Pancreatitis sponsored by CAPER. This study initiated by Georgios Papachristou, MD, Ph.D. Professor of Medicine at the University of Pittsburgh. The idea of creating a prospective international registry in Acute Pancreatitis developed during the PancreasFest 2014 (July 2014, Pittsburgh, PA). The University of Pittsburgh has led this initiative and served as the coordinating center. Dr. Papachristou in collaboration with Amir Gougol, internal medicine resident, designed and conducted the study and invited the investigators from highly experienced centers in pancreatic research.
In September 2015, the APPRENTICE phase I enrolled the first patient. Regular monthly/bi-weekly webinars, and multiple rounds of data quality monitoring performed under the guidance of Phil Greer, biostatistician, to ensure the quality of data. To date, more than 1500 patients from 24 centers throughout the world prospectively enrolled in the study.
Should you have any questions, please contact Georgios Papachristou at papachri@pitt.edu, Amir Gougol at gougolah@upmc.edu, or Phil Greer at pgreer@upmc.edu.
Participating Centers
On right, Georgios Papachristou, and on left Amir Gougol
Number of enrollment as of June 10th, 2017
APPRENTICE Progress
Publications/Grants
APPRENTICE Method Paper
Acute pancreatitis patient registry to examine novel therapies in clinical experience (APPRENTICE): an international, multicenter consortium for the study of acute pancreatitis.
Papachristou GI1, Machicado JD1, Stevens T2, Goenka MK3, Ferreira M4, Gutierrez SC5, Singh VK6, Kamal A6, Gonzalez-Gonzalez JA7, Pelaez-Luna M8, Gulla A9, Zarnescu NO10, Triantafyllou K11, Barbu ST12, Easler J13, Ocampo C14, Capurso G15, Archibugi L15, Cote GA16, Lambiase L17, Kochhar R18, Chua T2, Tiwari SC3, Nawaz H19, Park WG20, de-Madaria E21, Lee PJ22, Wu BU23, Greer PJ1, Dugum M1, Koutroumpakis E1, Akshintala V6, Gougol A1.
The method manuscript published in Annals of Gastroenterology and presented in DDW2010
Grant
UPP grant to support central biostatistician
Analysis and Publication Committee
In the webinar held on May 30, it was decided to assemble an “Analysis and Publication Committee”.
MEMBERS
Vikesh Singh, M.D.
Johns Hopkins Hospital, Baltimore, USA
Enrique de-Madaria, M.D.
Unidad Hospital General Universitario de Alicante, Alicante, Spain
Rakesh Kochhar, M.D.
Postgraduate Institute of Medical Education and Research, Chandigarh, India
Silvia C. Gutiérrez, M.D.
Hospital Nacional "Profesor A. Posadas", Buenos Aires, Argentina
Georgios I.Papachristou, M.D. Ph.D.
University of Pittsburgh, Pittsburgh, USA
Authorship Guidelines
UPDATED STUDY PROTOCOL
STUDY CONSENT FORM
UPMC IRB APPROVAL LETTER
DATA USE AGREEMENT